Products
IDE antibody
- Product Name
- IDE antibody
- Catalogue No.
- FNab04116
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- insulin-degrading enzyme
- UniProt ID
- P14735
- Observed MW
- 100-120 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04116(IDE antibody) at dilution of 1:300
IP Result of anti-IDE (IP:FNab04116, 4ug; Detection:FNab04116 1:500) with HepG2 cells lysate 1600ug.
Immunohistochemistry of paraffin-embedded human kidney using FNab04116(IDE antibody) at dilution of 1:50
- Background
- Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. (Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus(VZV).
